5DSG: Structure of the M4 muscarinic acetylcholine receptor (M4-mT4L) bound to tiotropium

PDB ID: 5DSGDownload
MMDB ID: 137481
PDB Deposition Date: 2015/9/17
Updated in MMDB: 2018/11
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Similar Structures:
Biological Unit for 5DSG: monomeric; determined by author
Molecular Components in 5DSG
Label Count Molecule
Protein (1 molecule)
1
Muscarinic Acetylcholine Receptor M4,endolysin,endolysin,muscarinic Acetylcholine Receptor M4
(Gene symbol: e)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
1
(1R,2R,4S,5S,7S)-7-{[hydroxy(dithiophen-2-yl)acetyl]oxy}-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.0~2,4~]nonane(1R,2R,4S,5S,7S)-7-{[hydroxy(dithiophen-2-yl)acetyl]oxy}-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.0~2,4~]nonane
2
3
OLEIC ACIDOLEIC ACID
3
1
{[-(BIS-CARBOXYMETHYL-AMINO)-ETHYL]-CARBOXYMETHYL-AMINO}-ACETIC ACID{[-(BIS-CARBOXYMETHYL-AMINO)-ETHYL]-CARBOXYMETHYL-AMINO}-ACETIC ACID
4
1
HEXAETHYLENE GLYCOLHEXAETHYLENE GLYCOL
5
4
(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303