5DS3: Crystal structure of constitutively active PARP-1

PDB ID: 5DS3Download
MMDB ID: 141286
PDB Deposition Date: 2015/9/16
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Similar Structures:
Biological Unit for 5DS3: monomeric; determined by author and by software (PISA)
Molecular Components in 5DS3
Label Count Molecule
Protein (1 molecule)
1
Poly [adp-ribose] Polymerase 1
(Gene symbol: PARP1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
PENTAETHYLENE GLYCOLPENTAETHYLENE GLYCOL
2
1
4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-one4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-one
3
2
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303