5DOH: Crystal structure of human carbonic anhydrase isozyme II with 2-[(1S)-2,3-Dihydro-1H-inden-1-ylamino]-3,5,6-trifluoro-4-[(2-hydroxyethyl)thio]benzenesulfonamide

PDB ID: 5DOHDownload
MMDB ID: 143466
PDB Deposition Date: 2015/9/11
Updated in MMDB: 2016/10
Experimental Method:
x-ray diffraction
Resolution: 1.05  Å
Source Organism:
Similar Structures:
Biological Unit for 5DOH: dimeric; determined by software (PISA)
Molecular Components in 5DOH
Label Count Molecule
Proteins (2 molecules)
2
Carbonic Anhydrase 2
(Gene symbol: CA2)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
2
ZINC IONZINC ION
2
2
BICINEBICINE
3
2
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
4
2
2-[(1S)-2,3-dihydro-1H-inden-1-ylamino]-3,5,6-trifluoro-4-[(2-hydroxyethyl)sulfanyl]benzenesulfonamide2-[(1S)-2,3-dihydro-1H-inden-1-ylamino]-3,5,6-trifluoro-4-[(2-hydroxyethyl)sulfanyl]benzenesulfonamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303