5DLW: Crystal structure of Autotaxin (ENPP2) with tauroursodeoxycholic acid (TUDCA) and lysophosphatidic acid (LPA)

PDB ID: 5DLWDownload
MMDB ID: 138354
PDB Deposition Date: 2015/9/7
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 5DLW: monomeric; determined by author and by software (PISA)
Molecular Components in 5DLW
Label Count Molecule
Protein (1 molecule)
1
Ectonucleotide Pyrophosphatase/phosphodiesterase Family Member 2
(Gene symbol: Enpp2)
Molecule annotation
Chemicals and Non-standard biopolymers (31 molecules)
1
2
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
beta-D-mannopyranosebeta-D-mannopyranose
3
4
alpha-D-mannopyranosealpha-D-mannopyranose
4
2
ZINC IONZINC ION
5
1
CALCIUM IONCALCIUM ION
6
1
(2R)-2-hydroxy-3-(phosphonooxy)propyl (9E)-octadec-9-enoate(2R)-2-hydroxy-3-(phosphonooxy)propyl (9E)-octadec-9-enoate
7
1
2-{[(3alpha,5beta,7alpha,8alpha,14beta,17alpha)-3,7-dihydroxy-24-oxocholan-24-yl]amino}ethanesulfonic acid2-{[(3alpha,5beta,7alpha,8alpha,14beta,17alpha)-3,7-dihydroxy-24-oxocholan-24-yl]amino}ethanesulfonic acid
8
2
SODIUM IONSODIUM ION
9
13
IODIDE IONIODIDE ION
10
2
THIOCYANATE IONTHIOCYANATE ION
11
2
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303