5DIG: Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a trifluoromethyl-substituted A-CD ring estrogen derivative (1S,3aR,5S,7aS)-5-[4-hydroxy-2-(trifluoromethyl)phenyl]-7a-methyloctahydro-1H-inden-1-ol

PDB ID: 5DIGDownload
MMDB ID: 138832
PDB Deposition Date: 2015/9/1
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.24  Å
Source Organism:
Similar Structures:
Biological Unit for 5DIG: tetrameric; determined by author and by software (PISA)
Molecular Components in 5DIG
Label Count Molecule
Proteins (4 molecules)
2
Estrogen Receptor
(Gene symbol: ESR1)
Molecule annotation
2
Nuclear Receptor Coactivator 2
(Gene symbol: NCOA2)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
(1S,3aR,5S,7aS)-5-[4-hydroxy-2-(trifluoromethyl)phenyl]-7a-methyloctahydro-1H-inden-1-ol(1S,3aR,5S,7aS)-5-[4-hydroxy-2-(trifluoromethyl)phenyl]-7a-methyloctahydro-1H-inden-1-ol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303