5DEL: Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM59

PDB ID: 5DELDownload
MMDB ID: 150341
PDB Deposition Date: 2015/8/25
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 5DEL: monomeric; determined by author and by software (PISA)
Molecular Components in 5DEL
Label Count Molecule
Protein (1 molecule)
1
Dihydroorotate Dehydrogenase (Quinone), Mitochondrial
(Gene symbol: PF3D7_0603300)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
FLAVIN MONONUCLEOTIDEFLAVIN MONONUCLEOTIDE
2
1
OROTIC ACIDOROTIC ACID
3
1
N-(3,5-dichlorophenyl)-2-methyl-3-nitrobenzamideN-(3,5-dichlorophenyl)-2-methyl-3-nitrobenzamide
4
2
GLYCEROLGLYCEROL
5
1
LAURYL DIMETHYLAMINE-N-OXIDELAURYL DIMETHYLAMINE-N-OXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303