5DDA: Menin in complex with MI-333

PDB ID: 5DDADownload
MMDB ID: 132552
PDB Deposition Date: 2015/8/24
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 1.83  Å
Source Organism:
Similar Structures:
Biological Unit for 5DDA: monomeric; determined by author and by software (PISA)
Molecular Components in 5DDA
Label Count Molecule
Protein (1 molecule)
1
Menin
(Gene symbol: MEN1)
Molecule annotation
Chemicals and Non-standard biopolymers (13 molecules)
1
1
4-{4-[5-(fluoromethyl)-1,3,4-thiadiazol-2-yl]piperazin-1-yl}-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidine4-{4-[5-(fluoromethyl)-1,3,4-thiadiazol-2-yl]piperazin-1-yl}-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidine
2
4
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
3
2
TRIETHYLENE GLYCOLTRIETHYLENE GLYCOL
4
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
5
5
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303