5DAF: Crystal Structure of Human KEAP1 BTB Domain in Complex with Small Molecule TX64063

PDB ID: 5DAFDownload
MMDB ID: 142070
PDB Deposition Date: 2015/8/19
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.37  Å
Source Organism:
Similar Structures:
Biological Unit for 5DAF: dimeric; determined by author and by software (PISA)
Molecular Components in 5DAF
Label Count Molecule
Proteins (2 molecules)
2
Kelch-like Ech-associated Protein 1
(Gene symbol: KEAP1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
(5aS,6S,9aS)-7-hydroxy-2,6,9a-trimethyl-3-(pyridin-3-yl)-4,5,5a,6,9,9a-hexahydro-2H-benzo[g]indazole-8-carbonitrile(5aS,6S,9aS)-7-hydroxy-2,6,9a-trimethyl-3-(pyridin-3-yl)-4,5,5a,6,9,9a-hexahydro-2H-benzo[g]indazole-8-carbonitrile
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303