5D7P: Crystal structure of human Sirt2 in complex with ADPR and EX-243

PDB ID: 5D7PDownload
MMDB ID: 134563
PDB Deposition Date: 2015/8/14
Updated in MMDB: 2015/12
Experimental Method:
x-ray diffraction
Resolution: 1.76  Å
Source Organism:
Similar Structures:
Biological Unit for 5D7P: dimeric; determined by author and by software (PISA)
Molecular Components in 5D7P
Label Count Molecule
Proteins (2 molecules)
2
Nad-dependent Protein Deacetylase Sirtuin-2
(Gene symbol: SIRT2)
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
2
ZINC IONZINC ION
2
2
[(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE[(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE
3
4
(1S)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1- carboxamide(1S)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1- carboxamide
4
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303