5CXZ: SYK catalytic domain complexed with naphthyridine inhibitor

PDB ID: 5CXZDownload
MMDB ID: 132714
PDB Deposition Date: 2015/7/29
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 1.7  Å
Source Organism:
Similar Structures:
Biological Unit for 5CXZ: monomeric; determined by author and by software (PISA)
Molecular Components in 5CXZ
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Kinase SYK
(Gene symbol: SYK)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
GLYCEROLGLYCEROL
2
1
CHLORIDE IONCHLORIDE ION
3
1
N-{7-[4-(dimethylamino)phenyl]-1,6-naphthyridin-5-yl}propane-1,3-diamineN-{7-[4-(dimethylamino)phenyl]-1,6-naphthyridin-5-yl}propane-1,3-diamine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303