5CUU: Crystal structure of Trypanosoma cruzi Vacuolar Soluble Pyrophosphatases in complex with bisphosphonate inhibitor BPH-1260

PDB ID: 5CUUDownload
MMDB ID: 136986
PDB Deposition Date: 2015/7/25
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.96  Å
Source Organism:
Similar Structures:
Biological Unit for 5CUU: tetrameric; determined by author and by software (PISA)
Molecular Components in 5CUU
Label Count Molecule
Proteins (4 molecules)
4
Acidocalcisomal Pyrophosphatase
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
6
D-MALATED-MALATE
2
4
1-butyl-3-(2-hydroxy-2,2-diphosphonoethyl)-1H-imidazol-3-ium1-butyl-3-(2-hydroxy-2,2-diphosphonoethyl)-1H-imidazol-3-ium
3
2
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303