5CUH: Crystal structure MMP-9 complexes with a constrained hydroxamate based inhibitor LT4

PDB ID: 5CUHDownload
MMDB ID: 136387
PDB Deposition Date: 2015/7/24
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.83  Å
Source Organism:
Similar Structures:
Biological Unit for 5CUH: monomeric; determined by author
Molecular Components in 5CUH
Label Count Molecule
Protein (1 molecule)
1
Matrix Metalloproteinase-9,matrix Metalloproteinase-9
(Gene symbol: MMP9)
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
2
ZINC IONZINC ION
2
3
CALCIUM IONCALCIUM ION
3
1
(4S)-3-{[4-(4-cyano-2-methylphenyl)piperazin-1-yl]sulfonyl}-N-hydroxy-1,3-thiazolidine-4-carboxamide(4S)-3-{[4-(4-cyano-2-methylphenyl)piperazin-1-yl]sulfonyl}-N-hydroxy-1,3-thiazolidine-4-carboxamide
4
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
5
1
S-1,2-PROPANEDIOLS-1,2-PROPANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303