5CR5: X-RAY CRYSTAL STRUCTURE AT 1.61A RESOLUTION OF HUMAN MITOCHONDRIAL BRANCHED CHAIN AMINOTRANSFERASE (BCATM) COMPLEXED WITH A BIPHENYL PYRROLIDINE ETHER COMPOUND AND AN INTERNAL ALDIMINE LINKED PLP COFACTOR

PDB ID: 5CR5Download
MMDB ID: 131797
PDB Deposition Date: 2015/7/22
Updated in MMDB: 2015/09
Experimental Method:
x-ray diffraction
Resolution: 1.61  Å
Source Organism:
Similar Structures:
Biological Unit for 5CR5: dimeric; determined by author and by software (PISA)
Molecular Components in 5CR5
Label Count Molecule
Proteins (2 molecules)
2
Branched-chain-amino-acid Aminotransferase, Mitochondrial
(Gene symbol: BCAT2)
Molecule annotation
Chemicals and Non-standard biopolymers (13 molecules)
1
2
PYRIDOXAL-5'-PHOSPHATEPYRIDOXAL-5'-PHOSPHATE
2
2
3-({(3R)-1-[(5-bromothiophen-2-yl)carbonyl]pyrrolidin-3-yl}oxy)-N-methyl-2'-[(methylsulfonyl)amino]biphenyl-4-carboxamide3-({(3R)-1-[(5-bromothiophen-2-yl)carbonyl]pyrrolidin-3-yl}oxy)-N-methyl-2'-[(methylsulfonyl)amino]biphenyl-4-carboxamide
3
2
CHLORIDE IONCHLORIDE ION
4
6
1,2-ETHANEDIOL1,2-ETHANEDIOL
5
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303