5CMK: Crystal structure of the GluK2EM LBD dimer assembly complex with glutamate and LY466195

PDB ID: 5CMKDownload
MMDB ID: 140689
PDB Deposition Date: 2015/7/16
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.801  Å
Source Organism:
Similar Structures:
Biological Unit for 5CMK: dimeric; determined by author and by software (PISA)
Molecular Components in 5CMK
Label Count Molecule
Proteins (2 molecules)
2
Glutamate Receptor Ionotropic, Kainate 2
(Gene symbol: Grik2)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
1
GLUTAMIC ACIDGLUTAMIC ACID
2
2
LITHIUM IONLITHIUM ION
3
2
CHLORIDE IONCHLORIDE ION
4
1
(3S,4aR,6S,8aR)-6-{[(2S)-2-carboxy-4,4-difluoropyrrolidin-1-yl]methyl}decahydroisoquinoline-3-carboxylic acid(3S,4aR,6S,8aR)-6-{[(2S)-2-carboxy-4,4-difluoropyrrolidin-1-yl]methyl}decahydroisoquinoline-3-carboxylic acid
5
2
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303