5CJO: Crystal Structure Analysis of Elbow-Engineered-Fab-Bound Human Insulin Degrading Enzyme (IDE) in Complex with Insulin

PDB ID: 5CJODownload
MMDB ID: 140678
PDB Deposition Date: 2015/7/14
Updated in MMDB: 2022/11
Experimental Method:
x-ray diffraction
Resolution: 3.287  Å
Source Organism:
Mus musculus▼
Similar Structures:
Biological Unit for 5CJO: octameric; determined by author
Molecular Components in 5CJO
Label Count Molecule
Proteins (8 molecules)
2
Insulin-degrading Enzyme
Molecule annotation
2
FAB Heavy Chain With Engineered Elbow
Molecule annotation
2
FAB Light Chain
Molecule annotation
2
Insulin
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
2
2
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303