5CGJ: Crystal structure of murine Keap1 in complex with RA839, a non-covalent small-molecule binder to Keap1 and selective activator of Nrf2 signalling

PDB ID: 5CGJDownload
MMDB ID: 133569
PDB Deposition Date: 2015/7/9
Updated in MMDB: 2015/12
Experimental Method:
x-ray diffraction
Resolution: 3.36  Å
Source Organism:
Similar Structures:
Biological Unit for 5CGJ: monomeric; determined by author and by software (PISA)
Molecular Components in 5CGJ
Label Count Molecule
Protein (1 molecule)
1
Kelch-like Ech-associated Protein 1
(Gene symbol: Keap1)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
4
SULFATE IONSULFATE ION
2
1
(3S)-1-(4-{[(2,3,5,6-tetramethylphenyl)sulfonyl]amino}naphthalen-1-yl)pyrrolidine-3-carboxylic acid(3S)-1-(4-{[(2,3,5,6-tetramethylphenyl)sulfonyl]amino}naphthalen-1-yl)pyrrolidine-3-carboxylic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303