5CEO: DLK in complex with inhibitor 2-((6-(3,3-difluoropyrrolidin-1-yl)-4-(1-(oxetan-3-yl)piperidin-4-yl)pyridin-2-yl)amino)isonicotinonitrile

PDB ID: 5CEODownload
MMDB ID: 133356
PDB Deposition Date: 2015/7/7
Updated in MMDB: 2015/11
Experimental Method:
x-ray diffraction
Resolution: 2.28  Å
Source Organism:
Similar Structures:
Biological Unit for 5CEO: monomeric; determined by author and by software (PISA)
Molecular Components in 5CEO
Label Count Molecule
Protein (1 molecule)
1
Mitogen-activated Protein Kinase Kinase Kinase 12
(Gene symbol: MAP3K12)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
2-[[6-[3,3-bis(fluoranyl)pyrrolidin-1-yl]-4-[1-(oxetan-3-yl)piperidin-4-yl]pyridin-2-yl]amino]pyridine-4-carbonitrile2-[[6-[3,3-bis(fluoranyl)pyrrolidin-1-yl]-4-[1-(oxetan-3-yl)piperidin-4-yl]pyridin-2-yl]amino]pyridine-4-carbonitrile
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303