5CCM: Crystal structure of SMYD3 with SAM and EPZ030456

PDB ID: 5CCMDownload
MMDB ID: 132488
PDB Deposition Date: 2015/7/2
Updated in MMDB: 2015/09
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 5CCM: monomeric; determined by author and by software (PISA)
Molecular Components in 5CCM
Label Count Molecule
Protein (1 molecule)
1
Histone-lysine N-methyltransferase Smyd3
(Gene symbol: SMYD3)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
3
ZINC IONZINC ION
2
1
S-ADENOSYLMETHIONINES-ADENOSYLMETHIONINE
3
1
6-chloranyl-2-oxidanylidene-N-[(1S,5R)-8-[4-[(phenylmethyl)amino]piperidin-1-yl]sulfonyl-8-azabicyclo[3.2.1]octan-3-yl]-1,3-dihydroindole-5-carboxamide6-chloranyl-2-oxidanylidene-N-[(1S,5R)-8-[4-[(phenylmethyl)amino]piperidin-1-yl]sulfonyl-8-azabicyclo[3.2.1]octan-3-yl]-1,3-dihydroindole-5-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303