5CB4: Crystal structure of T2R-TTL-Tivantinib complex

PDB ID: 5CB4Download
MMDB ID: 133913
PDB Deposition Date: 2015/6/30
Updated in MMDB: 2015/11
Experimental Method:
x-ray diffraction
Resolution: 2.193  Å
Source Organism:
Sus barbatus▼
Similar Structures:
Biological Unit for 5CB4: hexameric; determined by author
Molecular Components in 5CB4
Label Count Molecule
Proteins (6 molecules)
2
Tubulin Alpha
Molecule annotation
2
Tubulin Beta
Molecule annotation
1
Stathmin-4
Molecule annotation
1
Uncharacterized Protein
Molecule annotation
Chemicals and Non-standard biopolymers (14 molecules)
1
2
GUANOSINE-5'-TRIPHOSPHATEGUANOSINE-5'-TRIPHOSPHATE
2
3
MAGNESIUM IONMAGNESIUM ION
3
2
CALCIUM IONCALCIUM ION
4
1
GLYCEROLGLYCEROL
5
2
GUANOSINE-5'-DIPHOSPHATEGUANOSINE-5'-DIPHOSPHATE
6
1
2-(N-MORPHOLINO)-ETHANESULFONIC ACID2-(N-MORPHOLINO)-ETHANESULFONIC ACID
7
2
(3R,4R)-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione(3R,4R)-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione
8
1
PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTERPHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303