National Center for
Biotechnology Information

5C4X: Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble

PDB ID:

MMDB ID:

132127

PDB Deposition Date:

2015/6/18

Updated in MMDB:

2023/10

Experimental Method:

x-ray diffraction

Resolution:

4 Å

Source Organism:

Saccharomyces cerevisiae S288C▼

Taxonomy	Molecule
Saccharomyces cerevisiae S288C	A, B, C, D, E, F, G, H, I, J, K, L
synthetic construct	R, S, U

Similar Structures:

Biological Unit for 5C4X: 15-meric; determined by author

Molecular Components in 5C4X
Label	Count	Molecule
Proteins (12 molecules)
A	1	DNA-directed RNA Polymerase II Subunit Rpb1
B	1	DNA-directed RNA Polymerase II Subunit Rpb2
C	1	DNA-directed RNA Polymerase II Subunit Rpb3
D	1	DNA-directed RNA Polymerase II Subunit Rpb4
E	1	DNA-directed RNA Polymerases I, II, and III Subunit Rpabc1
F	1	DNA-directed RNA Polymerases I, II, and III Subunit Rpabc2
G	1	DNA-directed RNA Polymerase II Subunit Rpb7
H	1	DNA-directed RNA Polymerases I, II, and III Subunit Rpabc3
I	1	DNA-directed RNA Polymerase II Subunit Rpb9
J	1	DNA-directed RNA Polymerases I, II, and III Subunit Rpabc5
K	1	DNA-directed RNA Polymerase II Subunit Rpb11
L	1	DNA-directed RNA Polymerases I, II, and III Subunit Rpabc4
Nucleotides(3 molecules)
R	1	RNA (5'-r(pupcpgpapgpapgpgp*a)-3')
S	1	Non-template Strand DNA (38-mer)
U	1	Template Strand DNA (40-mer)
Chemicals and Non-standard biopolymers (11 molecules)
1	9	ZINC ION
2	2	MAGNESIUM ION

* Click molecule labels to explore molecular sequence information.

Citing MMDB