5BWZ: Crystal structure of S39E HDAC8 in complex with Droxinostat

PDB ID: 5BWZDownload
MMDB ID: 139869
PDB Deposition Date: 2015/6/8
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.59  Å
Source Organism:
Similar Structures:
Biological Unit for 5BWZ: monomeric; determined by author and by software (PISA)
Molecular Components in 5BWZ
Label Count Molecule
Protein (1 molecule)
1
Histone Deacetylase 8
(Gene symbol: HDAC8)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
ZINC IONZINC ION
2
2
POTASSIUM IONPOTASSIUM ION
3
2
DroxinostatDroxinostat
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303