5BWX: X-ray Crystal Structure At 1.70a Resolution Of Human Mitochondrial Branched Chain Aminotransferase (bcatm) Complexed With A 4-chloro-2- Fluoro Substituted Pyrazolopyrimidinone Compound And An Internal Aldimine Linked Plp Cofactor

PDB ID: 5BWXDownload
MMDB ID: 130630
PDB Deposition Date: 2015/6/8
Updated in MMDB: 2015/07
Experimental Method:
x-ray diffraction
Resolution: 1.7  Å
Source Organism:
Similar Structures:
Biological Unit for 5BWX: dimeric; determined by software (PISA)
Molecular Components in 5BWX
Label Count Molecule
Proteins (2 molecules)
2
Branched-chain-amino-acid Aminotransferase, Mitochondrial(Gene symbol: BCAT2)
Molecule annotation
Chemicals (26 molecules)
1
2
Pyridoxal-5'-PhosphatePyridoxal-5'-Phosphate
2
2
5-Butyl-2-[(4-Chloro-2-Fluorobenzyl)amino]-7-Oxo-4,7-Dihydropyrazolo[1,5-A]pyrimidine-3-Carbonitrile5-Butyl-2-[(4-Chloro-2-Fluorobenzyl)amino]-7-Oxo-4,7-Dihydropyrazolo[1,5-A]pyrimidine-3-Carbonitrile
3
17
1,2-Ethanediol1,2-Ethanediol
4
2
Chloride IonChloride Ion
5
2
GlycerolGlycerol
6
1
Dimethyl SulfoxideDimethyl Sulfoxide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes.Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303
.