5BVW: Fragment-based Discovery Of Potent And Selective Ddr1/2 Inhibitors

PDB ID: 5BVWDownload
MMDB ID: 131537
PDB Deposition Date: 2015/6/5
Updated in MMDB: 2015/08
Experimental Method:
x-ray diffraction
Resolution: 1.94  Å
Source Organism:
Similar Structures:
Biological Unit for 5BVW: monomeric; determined by software (PISA)
Molecular Components in 5BVW
Label Count Molecule
Protein (1 molecule)
1
Epithelial Discoidin Domain-containing Receptor 1
(Gene symbol: DDR1)
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
8
Iodide IonIodide Ion
2
1
N-(2-Chloro-6-Methylphenyl)-2-({6-[4-(2-Hydroxyethyl)piperazin-1-Yl]-2-Methylpyrimidin-4-Yl}amino)-1,3-Thiazole-5-CarboxamideN-(2-Chloro-6-Methylphenyl)-2-({6-[4-(2-Hydroxyethyl)piperazin-1-Yl]-2-Methylpyrimidin-4-Yl}amino)-1,3-Thiazole-5-Carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303