5BT5: Crystal structure of BRD2 second bromodomain in complex with SGC-CBP30 chemical probe

PDB ID: 5BT5Download
MMDB ID: 130624
PDB Deposition Date: 2015/6/2
Updated in MMDB: 2015/07
Experimental Method:
x-ray diffraction
Resolution: 1.4  Å
Source Organism:
Similar Structures:
Biological Unit for 5BT5: monomeric; determined by author and by software (PISA)
Molecular Components in 5BT5
Label Count Molecule
Protein (1 molecule)
1
Bromodomain-containing Protein 2
(Gene symbol: BRD2)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
4
1,2-ETHANEDIOL1,2-ETHANEDIOL
2
1
2-[2-(3-chloro-4-methoxyphenyl)ethyl]-5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(2S)-2-(morpholin-4-yl)propyl]-1H-benzimidazole2-[2-(3-chloro-4-methoxyphenyl)ethyl]-5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(2S)-2-(morpholin-4-yl)propyl]-1H-benzimidazole
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303