5BQC: Crystal structure of Norrin in complex with the cysteine-rich domain of Frizzled 4 and sucrose octasulfate

PDB ID: 5BQCDownload
MMDB ID: 130618
PDB Deposition Date: 2015/5/28
Updated in MMDB: 2025/12
Experimental Method:
x-ray diffraction
Resolution: 3  Å
Source Organism:
Similar Structures:
Biological Unit for 5BQC: tetrameric; determined by software (PISA)
Molecular Components in 5BQC
Label Count Molecule
Proteins (4 molecules)
2
Frizzled-4
(Gene symbol: FZD4)
Molecule annotation
2
Norrin
(Gene symbol: NDP)
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
3
2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose
2
2
1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose
3
4
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303