5BML: ROCK 1 bound to a pyridine thiazole inhibitor

PDB ID: 5BMLDownload
MMDB ID: 130010
PDB Deposition Date: 2015/5/22
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 2.95  Å
Source Organism:
Similar Structures:
Biological Unit for 5BML: dimeric; determined by author and by software (PISA)
Molecular Components in 5BML
Label Count Molecule
Proteins (2 molecules)
2
Rho-associated Protein Kinase 1
(Gene symbol: ROCK1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
N-[4-(2-fluoropyridin-4-yl)thiophen-2-yl]-2-{3-[(methylsulfonyl)amino]phenyl}acetamideN-[4-(2-fluoropyridin-4-yl)thiophen-2-yl]-2-{3-[(methylsulfonyl)amino]phenyl}acetamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303