5B8I: Crystal structure of Calcineurin A and Calcineurin B in complex with FKBP12 and FK506 from Coccidioides immitis RS

PDB ID: 5B8IDownload
MMDB ID: 129530
PDB Deposition Date: 2015/5/3
Updated in MMDB: 2019/11
Experimental Method:
x-ray diffraction
Resolution: 1.85  Å
Source Organism:
Similar Structures:
Biological Unit for 5B8I: trimeric; determined by author
Molecular Components in 5B8I
Label Count Molecule
Proteins (3 molecules)
1
Serine/threonine-protein Phosphatase
(Gene symbol: CIMG_06667)
Molecule annotation
1
Calcineurin Subunit B, Variant
(Gene symbol: CIMG_02704)
Molecule annotation
1
Peptidylprolyl Isomerase
(Gene symbol: CIMG_08666)
Molecule annotation
Chemicals and Non-standard biopolymers (20 molecules)
1
1
ZINC IONZINC ION
2
1
FE (III) IONFE (III) ION
3
2
2-(N-MORPHOLINO)-ETHANESULFONIC ACID2-(N-MORPHOLINO)-ETHANESULFONIC ACID
4
11
1,2-ETHANEDIOL1,2-ETHANEDIOL
5
4
CALCIUM IONCALCIUM ION
6
1
8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303