5B8D: Crystal structure of a low occupancy fragment candidate (N-(4-Methyl-1,3-thiazol-2-yl)propanamide) bound adjacent to the ubiquitin binding pocket of the HDAC6 zinc-finger domain

PDB ID: 5B8DDownload
MMDB ID: 141240
PDB Deposition Date: 2016/6/14
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.05  Å
Source Organism:
Similar Structures:
Biological Unit for 5B8D: monomeric; determined by author and by software (PISA)
Molecular Components in 5B8D
Label Count Molecule
Protein (1 molecule)
1
Histone Deacetylase 6
(Gene symbol: HDAC6)
Molecule annotation
Chemicals and Non-standard biopolymers (43 molecules)
1
3
ZINC IONZINC ION
2
2
FORMIC ACIDFORMIC ACID
3
1
~{N}-(4-methyl-1,3-thiazol-2-yl)ethanamide~{N}-(4-methyl-1,3-thiazol-2-yl)ethanamide
4
36
Molecule information is not available.
5
1
SODIUM IONSODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303