5AXO: Crystal Structure of Metallo-beta-Lactamase SMB-1 Bound to Hydrolyzed Meropenem

PDB ID: 5AXODownload
MMDB ID: 139102
PDB Deposition Date: 2015/7/31
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.39  Å
Source Organism:
Similar Structures:
Biological Unit for 5AXO: monomeric; determined by author and by software (PISA)
Molecular Components in 5AXO
Label Count Molecule
Protein (1 molecule)
1
Metallo-beta-lactamase
Molecule annotation
Chemicals and Non-standard biopolymers (17 molecules)
1
2
ZINC IONZINC ION
2
10
SODIUM IONSODIUM ION
3
3
SULFATE IONSULFATE ION
4
1
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
5
1
(2~{S},3~{R},4~{S})-2-[(2~{S},3~{R})-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-[(3~{S},5~{S})-5-(dimethylcarbamoy l)pyrrolidin-3-yl]sulfanyl-3-methyl-3,4-dihydro-2~{H}-pyrrole-5-carboxylic acid(2~{S},3~{R},4~{S})-2-[(2~{S},3~{R})-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-[(3~{S},5~{S})-5-(dimethylcarbamoy l)pyrrolidin-3-yl]sulfanyl-3-methyl-3,4-dihydro-2~{H}-pyrrole-5-carboxylic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303