5AVL: Crystal structure of LXRalpha in complex with tert-butyl benzoate analog, compound 32b

PDB ID: 5AVLDownload
MMDB ID: 132102
PDB Deposition Date: 2015/6/17
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.8  Å
Source Organism:
Similar Structures:
Biological Unit for 5AVL: tetrameric; determined by author and by software (PISA)
Molecular Components in 5AVL
Label Count Molecule
Proteins (4 molecules)
2
Oxysterols Receptor Lxr-alpha
(Gene symbol: NR1H3)
Molecule annotation
2
Nuclear Receptor Coactivator 1
(Gene symbol: NCOA1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
2-[4-[4-[[2-[(2-methylpropan-2-yl)oxycarbonyl]-3-oxidanyl-4-(trifluoromethyl)phenyl]methoxy]phenyl]phenyl]ethanoic acid2-[4-[4-[[2-[(2-methylpropan-2-yl)oxycarbonyl]-3-oxidanyl-4-(trifluoromethyl)phenyl]methoxy]phenyl]phenyl]ethanoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303