5AR8: RIP2 Kinase Catalytic Domain (1 - 310) complex with Biphenylsulfonamide

PDB ID: 5AR8Download
MMDB ID: 133546
PDB Deposition Date: 2015/9/24
Updated in MMDB: 2015/12
Experimental Method:
x-ray diffraction
Resolution: 2.79  Å
Source Organism:
Similar Structures:
Biological Unit for 5AR8: dimeric; determined by author and by software (PISA)
Molecular Components in 5AR8
Label Count Molecule
Proteins (2 molecules)
2
Receptor-interacting Serine/threonine-protein Kinase 2
(Gene symbol: RIPK2)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
2,6-bis(fluoranyl)-N-[3-[5-[2-[(3-methylsulfonylphenyl)amino]pyrimidin-4-yl]-2-morpholin-4-yl-1,3-thiazol-4-yl]phenyl]benzenesulfonamide2,6-bis(fluoranyl)-N-[3-[5-[2-[(3-methylsulfonylphenyl)amino]pyrimidin-4-yl]-2-morpholin-4-yl-1,3-thiazol-4-yl]phenyl]benzenesulfonamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303