5AQX: Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues

PDB ID: 5AQXDownload
MMDB ID: 143661
PDB Deposition Date: 2015/9/22
Updated in MMDB: 2016/10
Experimental Method:
x-ray diffraction
Resolution: 2.12  Å
Source Organism:
Similar Structures:
Biological Unit for 5AQX: monomeric; determined by author and by software (PISA)
Molecular Components in 5AQX
Label Count Molecule
Protein (1 molecule)
1
Heat Shock 70 KDA Protein 1A
(Gene symbol: HSPA1A)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
(1R,2S,3R,5R)-3-((5-(benzyloxy)quinazolin-4-yl)amino)-5-(hydroxymethyl)cyclopentane-1,2-diol(1R,2S,3R,5R)-3-((5-(benzyloxy)quinazolin-4-yl)amino)-5-(hydroxymethyl)cyclopentane-1,2-diol
2
2
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
3
1
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303