5AQW: Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues

PDB ID: 5AQWDownload
MMDB ID: 143660
PDB Deposition Date: 2015/9/22
Updated in MMDB: 2016/10
Experimental Method:
x-ray diffraction
Resolution: 1.53  Å
Source Organism:
Similar Structures:
Biological Unit for 5AQW: monomeric; determined by author and by software (PISA)
Molecular Components in 5AQW
Label Count Molecule
Protein (1 molecule)
1
Heat Shock 70 KDA Protein 1A
(Gene symbol: HSPA1A)
Molecule annotation
Chemicals and Non-standard biopolymers (16 molecules)
1
1
(1S,2R,3R,5R)-3-(hydroxymethyl)-5-(quinazolin-4-ylamino)cyclopentane-1,2-diol(1S,2R,3R,5R)-3-(hydroxymethyl)-5-(quinazolin-4-ylamino)cyclopentane-1,2-diol
2
1
PHOSPHATE IONPHOSPHATE ION
3
1
(2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL(2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL
4
12
1,2-ETHANEDIOL1,2-ETHANEDIOL
5
1
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303