5AJX: Human Pfkfb3 In Complex With An Indole Inhibitor 3

PDB ID: 5AJXDownload
MMDB ID: 128819
PDB Deposition Date: 2015/2/27
Updated in MMDB: 2015/05
Experimental Method:
x-ray diffraction
Resolution: 2.58  Å
Source Organism:
Similar Structures:
Biological Unit for 5AJX: dimeric; determined by author and by software (PISA)
Molecular Components in 5AJX
Label Count Molecule
Proteins (2 molecules)
2
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
(Gene symbol: PFKFB3)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
2
Phosphonic AcidPhosphonic Acid
2
2
Phosphate IonPhosphate Ion
3
2
Fructose-6-PhosphateFructose-6-Phosphate
4
2
(2s)-N-[4-[3-Cyano-1-[(3,5-Dimethyl-1,2-Oxazol-4-Yl)methyl]indol-5-Yl]oxyphenyl]pyrrolidine-2-Carboxamide(2s)-N-[4-[3-Cyano-1-[(3,5-Dimethyl-1,2-Oxazol-4-Yl)methyl]indol-5-Yl]oxyphenyl]pyrrolidine-2-Carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303