5AIK: Human DYRK1A in complex with LDN-211898

PDB ID: 5AIKDownload
MMDB ID: 127367
PDB Deposition Date: 2015/2/15
Updated in MMDB: 2018/12
Experimental Method:
x-ray diffraction
Resolution: 2.7  Å
Source Organism:
Similar Structures:
Biological Unit for 5AIK: dimeric; determined by author and by software (PISA)
Molecular Components in 5AIK
Label Count Molecule
Proteins (2 molecules)
2
Dyrk1a Dual-specificity Tyrosine-phosphorylation Regulated Kinase 1A
(Gene symbol: DYRK1A)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
2
4-(7-METHOXY-1-(TRIFLUOROMETHYL)-9H-PYRIDO[3,4-B]INDOL-9-yl)butan-1-amine4-(7-METHOXY-1-(TRIFLUOROMETHYL)-9H-PYRIDO[3,4-B]INDOL-9-yl)butan-1-amine
2
6
PHOSPHATE IONPHOSPHATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303