5ADI: Structure of human nNOS R354A G357D mutant heme domain in complex with 7-(((5-((Methylamino)methyl)pyridin-3-yl)oxy)methyl)quinolin-2- amine

PDB ID: 5ADIDownload
MMDB ID: 133691
PDB Deposition Date: 2015/8/20
Updated in MMDB: 2015/11
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 5ADI: dimeric; determined by author and by software (PISA)
Molecular Components in 5ADI
Label Count Molecule
Proteins (2 molecules)
2
Nitric Oxide Synthase, Brain
(Gene symbol: NOS1)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
2
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
2
2
5,6,7,8-TETRAHYDROBIOPTERIN5,6,7,8-TETRAHYDROBIOPTERIN
3
3
7-[[5-[(methylideneamino)methyl]pyridin-3-yl]oxymethyl]quinolin-2-amine7-[[5-[(methylideneamino)methyl]pyridin-3-yl]oxymethyl]quinolin-2-amine
4
1
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303