5ACX: VIM-2-2, Discovery of novel inhibitor scaffolds against the metallo- beta-lactamase VIM-2 by SPR based fragment screening

PDB ID: 5ACXDownload
MMDB ID: 133899
PDB Deposition Date: 2015/8/18
Updated in MMDB: 2015/11
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 5ACX: dimeric; determined by author and by software (PQS)
Molecular Components in 5ACX
Label Count Molecule
Proteins (2 molecules)
2
Beta-lactamase
Molecule annotation
Chemicals and Non-standard biopolymers (14 molecules)
1
6
ZINC IONZINC ION
2
2
2-(4-fluorophenyl)carbonylbenzoic acid2-(4-fluorophenyl)carbonylbenzoic acid
3
2
HYDROXIDE IONHYDROXIDE ION
4
4
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303