5ACW: VIM-2-1, Discovery of novel inhibitor scaffolds against the metallo- beta-lactamase VIM-2 by SPR based fragment screening

PDB ID: 5ACWDownload
MMDB ID: 133898
PDB Deposition Date: 2015/8/18
Updated in MMDB: 2015/11
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 5ACW: monomeric; determined by author and by software (PISA)
Molecular Components in 5ACW
Label Count Molecule
Protein (1 molecule)
1
Beta-lactamase
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
3
ZINC IONZINC ION
2
2
4-methyl-5-(trifluoromethyl)-1,2,4-triazole-3-thiol4-methyl-5-(trifluoromethyl)-1,2,4-triazole-3-thiol
3
2
CHLORIDE IONCHLORIDE ION
4
1
HYDROXIDE IONHYDROXIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303