5A86: Structure of pregnane X receptor in complex with a Sphingosine 1- Phosphate Receptor 1 Antagonist

PDB ID: 5A86Download
MMDB ID: 133530
PDB Deposition Date: 2015/7/13
Updated in MMDB: 2015/10
Experimental Method:
x-ray diffraction
Resolution: 2.25  Å
Source Organism:
Similar Structures:
Biological Unit for 5A86: tetrameric; determined by author and by software (PISA)
Molecular Components in 5A86
Label Count Molecule
Proteins (4 molecules)
2
Nuclear Receptor Subfamily 1 Group I Member 2
(Gene symbol: NR1I2)
Molecule annotation
2
Nuclear Receptor Coactivator 1
(Gene symbol: NCOA1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
4-chloro-N-[(1R)-1-[1-ethyl-6-(trifluoromethyl)benzimidazol-2-yl]ethyl]benzenesulfonamide4-chloro-N-[(1R)-1-[1-ethyl-6-(trifluoromethyl)benzimidazol-2-yl]ethyl]benzenesulfonamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303