5A46: FGFR1 in complex with dovitinib

PDB ID: 5A46Download
MMDB ID: 131505
PDB Deposition Date: 2015/6/5
Updated in MMDB: 2015/08
Experimental Method:
x-ray diffraction
Resolution: 2.63  Å
Source Organism:
Similar Structures:
Biological Unit for 5A46: monomeric; determined by software (PISA)
Molecular Components in 5A46
Label Count Molecule
Protein (1 molecule)
1
Fibroblast Growth Factor Receptor 1 (Fms-related Tyrosine Kinase 2, Pfeiffer Syndrome), Isoform Cra_b
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
3
1,2-ETHANEDIOL1,2-ETHANEDIOL
2
1
4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one
3
2
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303