5A3T: Crystal structure of human PLU-1 (JARID1B) in complex with KDM5-C49 (2-(((2-((2-(dimethylamino)ethyl)(ethyl)amino)-2-oxoethyl)amino)methyl) isonicotinic acid)

PDB ID: 5A3TDownload
MMDB ID: 130201
PDB Deposition Date: 2015/6/2
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 5A3T: monomeric; determined by author and by software (PISA)
Molecular Components in 5A3T
Label Count Molecule
Protein (1 molecule)
1
Lysine-specific Demethylase 5B
(Gene symbol: KDM5B)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
1
ZINC IONZINC ION
2
1
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
3
1
2-{[(2-{[(E)-2-(dimethylamino)ethenyl](ethyl)amino}-2-oxoethyl)amino]methyl}pyridine-4-carboxylic acid2-{[(2-{[(E)-2-(dimethylamino)ethenyl](ethyl)amino}-2-oxoethyl)amino]methyl}pyridine-4-carboxylic acid
4
1
NICKEL (II) IONNICKEL (II) ION
5
7
1,2-ETHANEDIOL1,2-ETHANEDIOL
6
1
MANGANESE (II) IONMANGANESE (II) ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303