4ZZY: Structure of human PARP2 catalytic domain bound to an isoindolinone inhibitor

PDB ID: 4ZZYDownload
MMDB ID: 131742
PDB Deposition Date: 2015/4/15
Updated in MMDB: 2015/09
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 4ZZY: monomeric; determined by software (PISA)
Molecular Components in 4ZZY
Label Count Molecule
Protein (1 molecule)
1
Poly [adp-ribose] Polymerase 2
(Gene symbol: PARP2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
2-[1-(4,4-Difluorocyclohexyl)-piperidin-4-yl]-6-fluoro-3-oxo-2,3-dihydro-1H-isoindole-4-carboxamide2-[1-(4,4-Difluorocyclohexyl)-piperidin-4-yl]-6-fluoro-3-oxo-2,3-dihydro-1H-isoindole-4-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303