4ZZM: Human ERK2 in complex with an irreversible inhibitor

PDB ID: 4ZZMDownload
MMDB ID: 129667
PDB Deposition Date: 2015/4/10
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 1.89  Å
Source Organism:
Similar Structures:
Biological Unit for 4ZZM: monomeric; determined by author and by software (PISA)
Molecular Components in 4ZZM
Label Count Molecule
Protein (1 molecule)
1
Mitogen-activated Protein Kinase 1
(Gene symbol: MAPK1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
SULFATE IONSULFATE ION
2
1
7-ethylsulfonyl-N-(oxan-4-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-amine7-ethylsulfonyl-N-(oxan-4-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303