4ZY2: X-ray crystal structure of PfA-M17 in complex with hydroxamic acid-based inhibitor 10o

PDB ID: 4ZY2Download
MMDB ID: 137847
PDB Deposition Date: 2015/5/21
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 4ZY2: hexameric; determined by author and by software (PISA)
Molecular Components in 4ZY2
Label Count Molecule
Proteins (6 molecules)
6
Probable M17 Family Aminopeptidase
Molecule annotation
Chemicals and Non-standard biopolymers (56 molecules)
1
12
ZINC IONZINC ION
2
6
CARBONATE IONCARBONATE ION
3
13
SULFATE IONSULFATE ION
4
18
PENTAETHYLENE GLYCOLPENTAETHYLENE GLYCOL
5
6
N-[(1R)-2-(hydroxyamino)-2-oxo-1-(3',4',5'-trifluorobiphenyl-4-yl)ethyl]-2,2-dimethylpropanamideN-[(1R)-2-(hydroxyamino)-2-oxo-1-(3',4',5'-trifluorobiphenyl-4-yl)ethyl]-2,2-dimethylpropanamide
6
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303