4ZXY: FACTOR VIIA IN COMPLEX WITH THE INHIBITOR (2R)-2-[(1-aminoisoquinolin-6-yl)amino]-4,11-diazatricyclo[14.2.2.1~6,10~]henicosa-1(18),6(21),7,9,16,19-hexaene-3,12-dione

PDB ID: 4ZXYDownload
MMDB ID: 131150
PDB Deposition Date: 2015/5/20
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.06  Å
Source Organism:
Similar Structures:
Biological Unit for 4ZXY: dimeric; determined by author and by software (PISA)
Molecular Components in 4ZXY
Label Count Molecule
Proteins (2 molecules)
1
Coagulation Factor Viia Heavy Chain
(Gene symbol: F7)
Molecule annotation
1
Coagulation Factor Viia Light Chain
(Gene symbol: F7)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
(2R)-2-[(1-aminoisoquinolin-6-yl)amino]-4,11-diazatricyclo[14.2.2.1~6,10~]henicosa-1(18),6(21),7,9,16,19-hexaene-3,12-dione(2R)-2-[(1-aminoisoquinolin-6-yl)amino]-4,11-diazatricyclo[14.2.2.1~6,10~]henicosa-1(18),6(21),7,9,16,19-hexaene-3,12-dione
2
1
CALCIUM IONCALCIUM ION
3
3
SULFATE IONSULFATE ION
4
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303