4ZXX: FACTOR VIIA IN COMPLEX WITH THE INHIBITOR N-{3-[(2R)-1-{(2R)-2-[(1-aminoisoquinolin-6-yl)amino]-2-phenylacetyl}pyrrolidin-2-yl]-4-(propan-2-ylsulfonyl)phenyl}acetamide

PDB ID: 4ZXXDownload
MMDB ID: 131149
PDB Deposition Date: 2015/5/20
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Similar Structures:
Biological Unit for 4ZXX: dimeric; determined by author and by software (PISA)
Molecular Components in 4ZXX
Label Count Molecule
Proteins (2 molecules)
1
Coagulation Factor Viia Heavy Chain
(Gene symbol: F7)
Molecule annotation
1
Coagulation Factor Viia Light Chain
(Gene symbol: F7)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
N-{3-[(2R)-1-{(2R)-2-[(1-aminoisoquinolin-6-yl)amino]-2-phenylacetyl}pyrrolidin-2-yl]-4-(propan-2-ylsulfonyl)phenyl}acetamideN-{3-[(2R)-1-{(2R)-2-[(1-aminoisoquinolin-6-yl)amino]-2-phenylacetyl}pyrrolidin-2-yl]-4-(propan-2-ylsulfonyl)phenyl}acetamide
2
1
CALCIUM IONCALCIUM ION
3
3
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303