4ZX9: X-ray crystal structure of PfA-M17 in complex with hydroxamic acid-based inhibitor 10b

PDB ID: 4ZX9Download
MMDB ID: 137844
PDB Deposition Date: 2015/5/20
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Similar Structures:
Biological Unit for 4ZX9: hexameric; determined by author and by software (PISA)
Molecular Components in 4ZX9
Label Count Molecule
Proteins (6 molecules)
6
Probable M17 Family Aminopeptidase
Molecule annotation
Chemicals and Non-standard biopolymers (41 molecules)
1
6
N-[(1R)-1-(4-bromophenyl)-2-(hydroxyamino)-2-oxoethyl]-2,2-dimethylpropanamideN-[(1R)-1-(4-bromophenyl)-2-(hydroxyamino)-2-oxoethyl]-2,2-dimethylpropanamide
2
12
ZINC IONZINC ION
3
6
CARBONATE IONCARBONATE ION
4
2
GLYCEROLGLYCEROL
5
10
PENTAETHYLENE GLYCOLPENTAETHYLENE GLYCOL
6
3
SULFATE IONSULFATE ION
7
2
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303