4ZX8: X-ray crystal structure of PfA-M17 in complex with hydroxamic acid-based inhibitor 9b

PDB ID: 4ZX8Download
MMDB ID: 137843
PDB Deposition Date: 2015/5/20
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.7  Å
Source Organism:
Similar Structures:
Biological Unit for 4ZX8: hexameric; determined by author and by software (PISA)
Molecular Components in 4ZX8
Label Count Molecule
Proteins (6 molecules)
6
Probable M17 Family Aminopeptidase
Molecule annotation
Chemicals and Non-standard biopolymers (52 molecules)
1
6
tert-butyl [(1R)-1-(4-bromophenyl)-2-(hydroxyamino)-2-oxoethyl]carbamatetert-butyl [(1R)-1-(4-bromophenyl)-2-(hydroxyamino)-2-oxoethyl]carbamate
2
12
ZINC IONZINC ION
3
6
CARBONATE IONCARBONATE ION
4
5
GLYCEROLGLYCEROL
5
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
6
15
PENTAETHYLENE GLYCOLPENTAETHYLENE GLYCOL
7
7
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303