4ZWX: Engineered Carbonic Anhydrase IX mimic in complex with glucosyl sulfamate inhibitor

PDB ID: 4ZWXDownload
MMDB ID: 133673
PDB Deposition Date: 2015/5/19
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 1.696  Å
Source Organism:
Similar Structures:
Biological Unit for 4ZWX: monomeric; determined by author and by software (PISA)
Molecular Components in 4ZWX
Label Count Molecule
Protein (1 molecule)
1
Carbonic Anhydrase 2
(Gene symbol: CA2)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
ZINC IONZINC ION
2
2
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
3
1
(1S)-2,3,4,6-tetra-O-acetyl-1,5-anhydro-1-{[5-(sulfamoyloxy)pentyl]sulfamoyl}-D-allitol(1S)-2,3,4,6-tetra-O-acetyl-1,5-anhydro-1-{[5-(sulfamoyloxy)pentyl]sulfamoyl}-D-allitol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303