4ZWG: Crystal structure of the GTP-dATP-bound catalytic core of SAMHD1 phosphomimetic T592E mutant

PDB ID: 4ZWGDownload
MMDB ID: 132244
PDB Deposition Date: 2015/5/19
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 4ZWG: tetrameric; determined by author and by software (PISA)
Molecular Components in 4ZWG
Label Count Molecule
Proteins (4 molecules)
4
Deoxynucleoside Triphosphate Triphosphohydrolase Samhd1
(Gene symbol: SAMHD1)
Molecule annotation
Chemicals and Non-standard biopolymers (16 molecules)
1
8
2'-DEOXYADENOSINE 5'-TRIPHOSPHATE2'-DEOXYADENOSINE 5'-TRIPHOSPHATE
2
4
GUANOSINE-5'-TRIPHOSPHATEGUANOSINE-5'-TRIPHOSPHATE
3
4
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303